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Program
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| Sunday, November 11 |
9:00 am - 1:00 pm |
SATELITTE SYMPOSIUM: GLYCOBIOLOGY AND GLYCOCHEMISTRY CHALLENGES IN BIOTECHNOLOGY ($40 extra) Organized by Shekar Ganesa, Genzyme and Joseph Siemiatkoski, Biogen Idec |
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8:30 am - 5:30 pm |
SATELLITE MEETING: GLYCANS IN CELL COMMUNICATION
This satellite meeting is being held in conjunction with the annual meeting of the participating investigators of the Consortium for Functional Glycomics. Attendance is open to all interested scientists and is free of charge. Be sure to check the appropriate box on the online registration form. |
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7:00 - 7:10 pm |
CONFERENCE OPENING
Opening Remarks: Jacques U. Baenziger, President, Society for Glycobiology |
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7:10 - 9:00 pm |
SESSION I: GLYCOCONJUGATE BIOSYNTHESIS
Chair, Anant Menon, Cornell University, NY
- In vivo Roles for Mammalian Oligosaccharyltransferase Isoforms, Reid Gilmore, University of Massachusetts Medical School, MA
- Substrate Recognition by GPI Transamidase, Anant Menon, Cornell University, NY
- Coupling Polymerization, Chain Termination and Export in the Biosynthesis of Lipopolysaccharide O Antigens, Chris Whitfield, University of Guelph Ontario
- Mycobacterial Cell Wall Glycomics: Recent Revelations, Delphi Chatterjee, Colorado State University
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9:00 - 10:00 pm |
WELCOME RECEPTION |
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| Monday, November 12 |
8:30 - 10:20 am |
SESSION II: GLYCANS ARE REQUIRED FOR EUKARYOTIC DEVELOPMENT
Chair, Carlos B. Hirschberg, Boston University, MA
- The Nucleotide Sugar Transport/Antiport Cycle in Eukaryotic Development and Disease, Carlos B. Hirschberg, Boston University, MA
- Glycan-Matrix Interactions in Peripheral Nerve Development, David Carey, Geisinger Center, PA
- Regulation of Skeletal Morphogenesis by Sulphated Proteoglycans in Zebrafish, Henry Roehl, Sheffield University, UK
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10:45 am - 12:35 pm |
SESSION III: GLYCANS ARE REQUIRED FOR EUKARYOTIC DEVELOPMENT II
Chair, Carlos B. Hirschberg, Boston University, MA
- Novel Proteoglycans Play an Essential Role in Early C. elegans Development, Sara Olson, UCSD, CA
- Synaptic Heparin Sulfate Proteoglycans Signaling in drosophila, David Van Vactor, Harvard University, MA
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2:00 - 4:00 pm |
POSTERS and EXHIBITS |
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4:00 - 6:15 pm |
SESSION IV: PROTEIN FOLDING AND QUALITY CONTROL
Chair, Armando Parodi, Instituto Leloir, Argentina
- ER Resident Lectins and Glycosylhydrolases Determine the Fate of Newly Synthesized Glycoproteins, Maurizio Molinari, Institute for Research in Biomedicine, Bellinzona, Switzerland
- Carbohydrate-Mediated Protein Maturation and Quality Control in the Endoplasmic Reticulum, Dan Hebert, University of Massachusetts, Amherst
- Extensive Mannose Trimming and Mannosidase Compartmentalization in Glycoprotein ER-Associated Degradation, Gerardo Lederkremer, Tel Aviv University, Tel Aviv, Israel
- The Biophysics of Quality Control, Julio Caramelo, Instituto Leloir, Buenos Aires, Argentina
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| Tuesday, November 13 |
8:30 - 10:00 am |
SESSION V: BIOLOGY AND BIOCHEMISTRY OF SULFATASES
Chair, Steven Rosen, UCSF, CA
- Introductory Comments: Structure and Function of Sulfatases
- Sulfatases Modifying Factor-1 Trafficking through Cells: Implications for Sulfatases Activities, Maria Pia Cosma, Telethon Institute of Genetics and Medicine, Napoli, Italy
- Heparan Endosulfatases and teh Regulation of Matrix Signaling, Charles Emerson Jr., Boston Biomedical Research Institute, MA
- The Sulfs: Dynamic Regulators of Cell Signalling and Development via Heparan Sulfate Editing, Thomas Dierks, Bielefeld University, Bielefeld, Germany
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10:30 am - 12:30 pm |
SESSION VI: QUANTITATIVE GLYCOBIOLOGY
Chair, Jefrey Esko, UCSD, CA
- Mathematical Modeling of Biological Systems, Arthur D. Lander, University of California, Irvine
- Computational Simulations in Glycoscience: Predicting Affinities and Carbohydrate-Protein Structures, Robert J. Woods, CCRC, University of Georgia
- Chemical Glycobiology and Vaccine Development, Geert-Jan Boons, CCRC, University of Georgia
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2:00 - 4:00 pm |
POSTERS and EXHIBITS |
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4:00 - 4:30 pm |
BUSINESS MEETING |
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4:45 - 5:45 pm |
KARL MEYER LECTURE |
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7:00 - 9:30 pm |
BANQUET. Nominal fee. Extra tickets for guests may be ordered |
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| Wednesday, November 14 |
8:30 - 10:00 am |
SESSION VII: RECOGNITION IN GLYCANS BIOSYNTHESIS AND FUNCTION
Chair, Karen J. Colley, Univ. of Illinois-Chicago
- Sequence Requirements for NCAM Polysialylation, Karen Colley, Univ. of Illinois-Chicago
- Use of Lectins to Study the N-Glycomes of Giardia and Entamoeba, John Samuelson, Boston University, MA
- Non-Canonical Activation of Antigen Presenting Cells by a Helminth Glycan, Don Harn, Harvard University, MA
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10:30 am - 12:30 pm |
SESSION VIII: STRUCTURAL INSIGHTS OF PROTEIN-CARBOHYDRATE INTERACTIONS
Chair, Nancy Dahms, Medical College of Wisconsin
- Carbohydrate-Based Pharamcological Chaperones for Treatment of Lysosomal Storage Diseases, Gregory A. Petsko, Brandeis University, MA
- Role of Heparin & Heparan Sulfate on Proteins of the Hedgehog Signaling Pathway, Robert Linhardt, Rensselaer Polytechnic Institute, NY
- A Model for Processive Glycan Chain Synthesis, Suzanne Walker, Harvard University, MA
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2:00 - 4:00 pm |
SESSION IX: GLYCOSYLATION IN THE CYTOSOL
Chair, John Hanover, National Institute of Health, MD
- SECRET AGENT and SPY inform about the Role of Protein O-GlcNAc Modification in Plant Processes, Neil Olszewski, University of Minnesota
- Breaking the O-glcNAc Code: O-glcNAc and Cellular Signaling, Dona Love, National Institute of Health, MD
- Significance of Cytoplasmic Glycosylation for O2-Signaling in Dictyostelium and Other Protists, Christopher West, Oklahoma University Health Science Center
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4:00- 6:00 pm |
POSTERS and EXHIBITS |
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Satellite Symposium
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Sunday, November 11
9 am – 1 pm
Satellite Symposium: Glycobiology and Glycochemistry Challenges in Biotechnology
($40 extra) Organized by Shekar Ganesa, Genzyme and Joseph Siemiatkoski, Biogen Idec
9:00 - 9:25 Increasing Antibody ADCC through Carbohydrate Modification with Glycosylation Inhibitors, Qun Zhou, Genzyme Corporation, Framingham, MA
9:25 - 9:50 Tackling N-Glycan Heterogeneity: Glyco-Optimization of Therapeutic Glycoproteins in Lemna, Jason Sterling, Biolex Therapeutics, Pittsboro, NC
9:50 - 10:15 The Importance of Monitoring, Maintaining and Analyzing Sialic Acids on Therapeutic Proteins, Tom Warner, Prozyme, San Leandro, CA
10:15 - 10:40 Characterization of Glycan Structures of a Lysosomal Enzyme and Correlation with Biological Activity, Victor Chan, Shire HGT, Cambridge, MA
10:40 – 11:10 BREAK
11:10 - 11:35 2D-LC MS Analysis of Bioreactor Samples, Zoran Sosic, Biogen-Idec, Cambridge, MA
11:35 - 12:00 Uncovering Unique Structural Isomers in Cancer via MSn Disassembly, Justin M Prien, University of New Hampshire, Durham, NH
12:00 - 12:25 Challenges in Structural Charcterization of Heparin and GAG containing Polysaccharides, Parastoo Azadi, Complex Carbohydrate Research Center, Athens, GA
12:25 - 12:50
Discussion
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Satelitte Meeting
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Printable program agenda
This satellite meeting is being held in conjunction with the annual meeting of the participating investigators of the Consortium for Functional Glycomics. Attendance is open to all interested scientists and is free of charge. For a full agenda please click here.
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