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| Wednesday,
December 3 |
| 7:00 - 7:15 pm |
CONFERENCE OPENING
Opening Remarks: Jeffrey Esko, President, Society for Glycobiology |
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| 7:15 - 8:45 pm |
SESSION I: CARBOHYDRATE DIVERSITY
Chair: Gerald W. Hart, Johns Hopkins School of Medicine |
| 7:15 pm | - James C. Paulson, The Scripps Research Institute
Microarray analysis of glycosyltransferase gene expression
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| 7:40 pm | - Catherine E Costello, Boston University School of Medicine
Mass Spectrometry-Based Methods for Revealing the Glycans’ Family Secrets
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| 8:05 pm | - Chi-Huey Wong, Scripps Research Institute
Glycosylation techniques for generating carbohydrate diversity
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| 8:30 pm | - Balagurunathan Kuberan, MIT
Heparanomics: A Voyage to Establish the Foundation of Glycobiology?
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| 8:35 pm | - Steven B. Levery, University of New Hampshire
Application of ion trap MSn strategies to structure elucidation of diverse glycosylinositols derived from fungal glycosphingolipids
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| 8:40 pm | - Richard A. Alvarez, University of Oklahoma Health Sciences Center
High Throughput Glycan Array Analysis of Human Galectins-1 and –4.
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| 8:45 - 10:00 pm |
RECEPTION |
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| Thursday,
December 4 |
| 8:30 - 10:00 am |
SESSION II: GLYCOBIOLOGY AND INFECTION
Chair: Marilynn Etzler, University of California, Davis |
| 8:30 am | - Tamara L. Doering, Washington University Medical School
Capsule synthesis in the pathogenic fungus Cryptococcus neoformans
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| 8:55 am | - Pyong Woo Park, Baylor College of Medicine
Regulation of Tissue Injury and Inflammation by Syndecan-1 Ectodomain Shedding
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| 9:20 am | - Salvatore J. Turco, University of Kentucky
Reconstitution of GDP-Man Transport Activity with Purified Leishmania LPG2 Protein in Proteoliposomes ID=71">
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| 9:45 am | - Benhur Lee, UCLA
Cell fusion and syncytia formation is mediated by oligosaccharide determinants of Nipah virus envelope F and G glycoproteins and can be blocked by lectins ID=62">
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| 9:50 am | - Irma van Die, VU University Medical Center, Amsterdam, the Netherlands
LacdiNAc glycans constitute a parasite pattern for galectin-3-mediated immune recognition.
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| 9:55 am | - A. Kwame Nyame, University of Oklahoma Health Sciences Center
Glycoproteins from Soluble Egg Antigens are the Major Antigens for Stimulation of Anti-glycan Antibody Responses in Primary Schistosoma mansoni Infections.
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| 10:00 - 10:30 am |
Break and Exhibits |
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| 10:30 am - 12:25 pm |
SESSION III: GLYCOBIOLOGY AND CELL BIOLOGY
Chair: Ajit Varki, University of California, San Diego |
| 10:30 am | - Carlos B Hirschberg, Boston University Goldman School of Dental Medicine
The Nucleotide Sugar/Antiport System: What New Concepts Can We Learn From C. elegans?
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| 10:55 am | - Richard N. Sifers, Baylor College of Medicine
Molecular and Cellular Biology of Glycoprotein Quality Control ID=72">
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| 11:20 am | - John J. Bergeron, McGill University
The calnexin cycle in productive glycoprotein folding and quality control
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| 11:45 am | - Stuart Kornfeld, Washington University School of Medicine
The GGA Family of Coat Proteins Play a Critical Role in the Man-6-P Targeting Pathway
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| 12:10 pm | - Samiksha Katiyar , State University of New York at Stony Brook, NY
NUCLEAR LOCALIZATION OF A CYTOSOLIC DEGLYCOSYLATING ENZYME PEPTIDE:N-GLYCANASE (PNGase): EXPLORATION OF POSSIBLE FUNCTIONS OF PNGase IN THE NUCLEUS
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| 12:15 pm | - Natasha E Zachara, Dept. Biological Chemistry, Johns Hopkins University School of Medicine
O-GlcNAc: A New Paradigm for Modulating Cellular Responses to Stress.
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| 12:20 pm | - Hudson H. Freeze, The Burnham Institute
Cog1 and Cog2 deficiencies prevent normal nucleotide sugar transport and decrease multiple glycosyltransferase activities
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| 12:25 - 2:00 pm |
Lunch Break |
| 2:00 - 4:00 pm |
POSTERS and EXHIBITS |
| 3:00 - 4:00 pm |
WORKSHOP: Informatics. Anne Dell, Imperial
College
Index of presentations (Powerpoints)
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| 4:00 - 5:55 pm |
SESSION IV: GLYCANS IN PHYSIOLOGIC
PROCESSES
Chair: Jamey Marth, HHMI, University of California, San Diego |
| 4:00 pm | - Marilynn E. Etzler, University of California, Davis
Perception of the glycan signals that initiate the Rhizobium-legume symbiosis.
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| 4:25 pm | - Paul Noble, Yale University
Hyaluronan and CD44 Regulation of Tissue Injury and Repair ID=90">
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| 4:50 pm | - Richard L. Proia, National Institute of Diabetes and Digestive and Kidney Diseases
Physiologic functions of gangliosides
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| 5:15 pm | - John B. Lowe, HHMI, University of Michigan
Fucosylation in the control of leukocyte biology
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| 5:40 pm | - Joseph TY Lau, Roswell Park Cancer Institute
Biologic contribution of ST6Gal I sialyltransferase in the early inflammatory response
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| 5:45 pm | - Mark G Wahrenbrock, Glycobiology Research and Training Center, University of California, San Diego
Selectin-mucin interactions: a probable molecular explanation for the association of Trousseau’s syndrome with mucinous adenocarcinomas
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| 5:50 pm | - Charles E. Warren, University of New Hampshire
Modeling CDG type I in Caenorhabditis elegans: A screen for modifying and glycosylation-dependent loci.
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| Friday,
December 5 |
| 8:30 - 10:00 am |
SESSION V: GLYCOBIOLOGY AND BIOCHEMISTRY
Chair: Chi-Huey Wong, The Scripps Research Institute |
| 8:30 am | - Ian A. Wilson, The Scripps Research Institute
Structural basis of glycolipid presentation by CD1
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| 8:55 am | - Masahiko Negishi, National Institutes of Health
Structure and function of glycosyltransferases
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| 9:20 am | - Stephen G Withers, University of British Columbia
New mechanisms for the enzymatic cleavage of oligosaccharides
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| 9:45 am | - Pablo Argüeso , Harvard Medical School
SIALIC ACID DERIVATIVES ON MUCINS OF THE OCULAR SURFACE
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| 9:50 am | - Corin Wing, University of East Anglia
Characterisation of WlbA (a putative 3-dehydrogenase) and WlbC (a putative 3-transaminase) two of the key enzymes involved in Bordtella pertussis UDP D-Man-diNAcA biosynthesis.
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| 9:55 am | - Yasuhiro Hashimoto, RIKEN Institute
In vivo cleavage and secretion of a2,6-sialyltransferase
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| 10:00 - 10:30 am |
Break and Exhibits |
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| 10:30 am - 12:25 pm |
SESSION VI: GLYCOBIOLOGY AND IMMUNITY
Chair, Minoru Fukuda, The Burnham Institute |
| 10:30 am | - Steven D. Rosen, University of California, San Francisco
Regulation of cell surface recognition events through sulfation: putting it on and taking it off
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| 10:55 am | - Paul Crocker, Dundee University
CD33-related siglecs in the innate immune system
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| 11:20 am | - Taroh Kinoshita, Osaka University, Osaka, Japan
Expression of GPI-anchored proteins: events post-attachment of the anchor en route to the cell surface ID=36">
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| 11:45 am | - Rodger P. McEver, Oklahoma Medical Research Foundation
Selectin-Dependent Leukocyte Interactions with Vascular Surfaces ID=88">
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| 12:10 pm | - Yuzuru IKEHARA, The Scripps Research Institute
Siglec-7 and Siglec-9 negatively regulate T cell receptor activation ID=89">
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| 12:15 pm | - Junya Mitoma, The Burnham Institute
The role of extended core 1 O-glycans in leukocyte trafficking: b1,3-N-Acetylglucosaminyltransferase-3 is essential for synthesis of MECA-79 antigen in lymph nodes and plays a role in lymphocyte adhesion to high endothelial venules
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| 12:20 pm | - Gary F. Clark, Eastern Virginia Medical School
Potent Suppression of Natural Killer Cell Response Mediated by the
Ovarian Tumor Marker CA125
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| 12:25 - 2:00 pm |
Lunch Break |
| 2:00 - 4:00 pm |
POSTERS and EXHIBITS |
| 3:00 - 4:00 pm |
DISCUSSION: Reinvention of Study
Sections and Your Grants
Jeffrey Esko and Gerald W. Hart |
| 4:00 - 5:00 pm |
BUSINESS MEETING |
| 5:00 - 5:55 pm |
KARL MEYER LECTURE |
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| Saturday,
December 6 |
| 8:30 - 10:00 am |
SESSION VII: CHEMICAL GLYCOBIOLOGY
Chair: Richard Cummings, University of Oklahoma Health Sciences Center |
| 8:30 am | - Ole Hindsgaul, Carlsberg Laboratory
Frontal Affinity Chromatography/Mass Spectrometry in the Screening of Mixtures: Towards Determining the Binding Constant of an Undetectable Compound of Unknown Concentration
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| 8:55 am | - Jon S. Thorson, University of Wisconsin, Madison
Lessons From Nature: Antibiotic Optimization via Glycorandomization
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| 9:20 am | - Carolyn R. Bertozzi, University of California, Berkeley
CHEMICAL APPROACHES TO STUDYING PROTEIN GLYCOSYLATION ID=93">
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| 9:45 am | - Yingming Zhao, UT Southwestern Medical Center
A novel technology for detection and proteomic analysis of O-GlcNAc modified proteins
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| 9:50 am | - Jamie R. Rich, University of Alberta
Glycosyltransferase Catalyzed Synthesis of Thiooligosaccharides
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| 9:55 am | - Paul L. DeAngelis, Univ. of Oklahoma Health Sciences Center
Chemoenzymatic Synthesis of Glycosaminoglycans with Pasteurella Synthases
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| 10:00 - 10:30 am |
Break and Exhibits |
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| 10:30 am - 12:25 pm |
SESSION VIII: GLYCOBIOLOGY AND DEVELOPMENT
Chair: Yu Yamaguchi, The Burnham Institute |
| 10:30 am | - H. Joseph Yost, Huntsman Cancer Institute, University of Utah
Syndecans control matrix deposition, substrate-dependent cell migration and cell non-autonomous Left-Right signaling
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| 10:55 am | - Victor D. Vacquier, University of California San Diego
Egg Carbohydrates Inducing the Acrosome Reaction in Sea Urchin Sperm ID=70">
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| 11:20 am | - Raffi V. Aroian, University of California, San Diego
Bt Toxin v. Worms: It all comes down to sugars
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| 11:45 am | - Kenneth Irvine, HHMI/Rutgers University
Regulation of Notch signaling by O-fucose glycans
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| 12:10 pm | - Sara K. Olson, University of California, San Diego
Chondroitin is required for C. elegans vulval development and embryogenesis
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| 12:15 pm | - Michael Tiemeyer, Complex Carbohydrate Research Center
Trans-cellular induction of neural-specific glycosylation by a Toll-like receptor
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| 12:20 pm | - Kazuhide Uemura, Albert Einstein College Medicine
Roles of O-Fucose Glycans in Ligand Binding to Mammalian Notch Receptors
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| 12:25 - 2:00 pm |
Lunch Break |
| 2:00 - 4:00 pm |
POSTERS and EXHIBITS |
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| 4:00 - 5:55 pm |
SESSION IX: GLYCOBIOLOGY AND PLASTICITY OF
NERVOUS AND MUSCULOSKELETAL SYSTEMS
Chair: Hudson Freeze, The Burnham Institute |
| 4:00 pm | - Ronald L. Schnaar, The Johns Hopkins School of Medicine
Glycobiology of neuronal regeneration in the adult CNS
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| 4:25 pm | - Urs Rutishauser, Memorial Sloan-Kettering Cancer Center
Polysialic Acid and Neural Plasticity ID=79">
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| 4:50 pm | - Yu Yamaguchi, The Burnham Institute
Broad yet surprisingly specific functions of heparan sulfate in mammalian brain development
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| 5:15 pm | - Kevin Campbell, University of Iowa College of Medicine
Glycosylation and dystroglycan function in muscular dystrophy
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| 5:40 pm | - Susan E. Sparks, National Institutes of Health
Hereditary Inclusion Body Myopathy; Epimerase activity, GNE mutations and treatment strategies
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| 5:45 pm | - Linjuan Huang, Michigan State University
Amylose, chitin and the glycopathobiochemistry of Alzheimer’s disease: A reevaluation of the origin, composition and significance of amyloid plaque.
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| 5:50 pm | - Keiko Kato, NIAST and RIKEN, Japan
Region-specific and epileptogenic-dependent expression of a2,3-sialyltransferase in the adult mouse brain.
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