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Post-Doctoral Fellow

Position: Post-Doctoral Fellow 
Organization: Food and Drug Administration Center for Biologics Evaluation and Research 
Location: Bethesda MD 
Date Posted: June 11, 2020 

The Food and Drug Administration Center for Biologics Evaluation and Research is seeking a motivated post-doctoral individual to join The Division of Bacterial, Parasitic & Allergenic Products Laboratory of Bacterial Polysaccharides Vaccine Structure Group. The successful candidate will work with an experienced research team to investigate the structural aspects of glycoconjugate based vaccines. 

The position will focus on mass spectrometry-based approaches for analysis of glycoproteins and other glycoconjugates particularly in the area of vaccine antigens. Glycan array technologies are also employed to study viral pathogen interactions with host glycoconjugate receptors. Key mass spectrometry work-flows investigate glycosylation on the peptide backbone to reveal location, composition, heterogeneity, glycan subclass, site occupancies, and relationship to antigen structure as well as potential targets of human lectin based innate immune factors. These studies facilitate a better understanding of how glycosylation can impact on vaccine performance and how glycosylation impacts the host-pathogen interface. 

This position requires a Ph. D. in chemistry, biochemistry, structural biology or a related science. New graduates are welcome to apply. A background in mass spectrometry is required. Experience in glycobiology, carbohydrate chemistry and/or proteomics mass spectrometry is a plus. The laboratory’s research crosses the boundaries between analytical chemistry, structural biology, biochemistry and microbiology. The laboratory develops state of the art mass spectrometric platforms for use in FDA mission critical projects centered on issues surrounding glycosylation of key vaccine antigens. Excellent communication skills (oral and written) and the ability to work in a team environment are required. 

Salary will be commensurate with qualifications and experience. To be considered for this position, please write or email your Curriculum vitae to: 

John F. Cipollo, Ph. D. 
Principal Investigator 
Center for Biologics Evaluation and Research 
Division of Bacterial, Parasitic and Allergenic Products 
Food and Drug Administration 
10903 New Hampshire Avenue 
Building # 52/72 and Room # G310 
Silver Spring, MD 20993-0002 
Office 240-402-9445