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The Wistar Institute, Philadelphia, USA

Role of Host Glycosylation Machinery in HIV Persistence and Immunopathogenesis

A Postdoctoral Fellow position for a highly motivated researcher is available in Dr. Mohamed Abdel-Mohsen Laboratory at The Wistar Institute. The Wistar Institute is an international leader in biomedical research founded in 1892 as the first independent biomedical research center in the United States. The Wistar Institute is located in the University City area of Philadelphia, in the heart of the University of Pennsylvania Campus. The Institute is worldrenowned for its cancer research and vaccine development. Wistar is one of the “Martin Delaney Collaboratory: Towards an HIV-1 Cure” funded sites (BEAT-HIV Collaboratory), and is part of the Penn Center for AIDS Research (Penn CFAR) with access to state-of-the-art facilities and an outstanding intellectual environment that enable faculty and staff members to conduct cutting-edge research.

The Abdel-Mohsen laboratory investigates the role of host glycosylation machinery in viral persistence and immunopathogenesis. The focus of the work will be a combination of approaches including: Investigate the role of glycan-lectin interactions and altered glycosylation in mediating cellular processes central to immune regulation; multi-omics approaches to study host immune response to HIV infection; and utilize humanized mouse model of HIV infection to examine the role of host glycosylation in viral pathogenies.

Preferred candidates would have experience in: translational research (working with human clinical specimens); glycomic, proteomics, and transcriptomic analyses; glycoimmunology; tissue culture; molecular cloning; flow cytometry; cellular immunology; and/or expertise working with humanized murine models.

Contact: Mohamed Abdel-Mohsen at