Meetings Program



Meeting theme: "Glycobiology research at the interface"

DAY 1: Saturday, Nov 2, 2019

08:00AM – 06:00PM     Registration
                                           Ballroom Foyer
09:00AM – 05:00PM   Satellite 1: Tools in Glycoscience (CLICK HERE FOR AGENDA)
                                           Session chairs: Richard Cummings (Harvard Medical School)
                                            and Robert Woods (CCRC)

                                           Maricopa Room
09:00AM – 01:00PM   Satellite 2: Glyco in Biotechnology (CLICK HERE FOR AGENDA)
                                           Session chair: Parastoo Azadi (University of Georgia, CCRC)
                                           Pima Room
12:00PM – 04:00PM          Board of Directors Meeting (by invitation only)
                                           Gila Room
05:30PM – 07:15PM   Opening Meyer and Kornfeld Awards Lectures
                                           North Ballroom
5:30PM - 5:45PM          Conference Opening Remarks
5:45PM - 6:30PM          Karl Meyer Award Lecture: Robert Linhardt (Rensselaer Polytechnic Institute)
6:30PM - 7:15PM          Rosalind Kornfeld Award Lecture: Nancy Dahms (Medical College of Wisconsin)
07:30PM – 09:30PM   Welcome Reception & Exhibits
                                           Pueblo Ballroom


DAY 2: Sunday, Nov 3, 2019

07:30AM – 02:00PM         Registration
                                           Ballroom Foyer
07:30AM – 08:30AM         Continental Breakfast
                                           Ballroom Foyer
08:30AM – 10:10AM  Session 1: Glycans and Evolution
                                           Session chair: Christopher West (University of Georgia, BCMB)
                                           North Ballroom
08:30AM – 08:55AM    Pascal Gagneux (UC San Diego) The Runaway Self” – Changing while remaining the same. #1
08:55AM – 09:20AM    Marco Sardiello (Baylor College of Medicine) – A Stepwise Mechanism for ER-to-Golgi Transport of Lysosomal Enzymes. #2
09:20AM – 09:45AM    Jerry Eichler (Ben Gurion University of the Negev, Israel) – N-glycosylation in Archaea: Extremely creative. #3
Poster Talks
09:45AM – 09:50AM    Rahil Taujale (University of Georgia) – Understanding the sequence-structure-function relationships through a comprehensive evolutionary analysis of GT-A fold glycosyltransferases. #4/B001
09:50AM – 09:55AM    Alan John (University of Melbourne) – Deciphering the molecular functions of tryptophan C-mannosylation. #5/B002
09:55AM – 10:00AM    Ishita Chandel (Texas A&M University) – Functional players of Protein O-mannosyltransferases 1/2 –mediated regulation of sensory neuron connectivity in Drosophila. #6/B003
10:00AM – 10:05AM    Camilo Perez (University of Basel, Biozentrum) – Structure and mechanism of a pH sensing lipoteichoic-acid-anchor flippase. #7/B004
10:05AM – 10:10AM    Sudeshna Saha (University of California San Diego) – Exploring Evolutionary Origins of Human-Specific CD33/Siglec-3 Alleles that Protect against Late Onset Alzheimer’s Disease: Prior Selection by Uniquely Human Pathogens? #8/B005
10:10AM – 10:30AM         Coffee Break
                                           Ballroom Foyer
10:30AM – 12:10PM   Session 2: Glycobiology of the Microbiome
                                           Session chair: Christine Szymanski (University of Georgia, MB)
                                           North Ballroom
10:30AM – 10:55AM    David Gerlach (University of Tübingen, Germany) – Staphylococcus aureus remodels surface glycopolmers to shape colonization and invasion capacities. #9
10:55AM – 11:20AM    Thierry Hennet (University of Zurich, Switzerland) – Prebiotic action of dietary and mucosal carbohydrates on the gut microbiota. #10
11:20AM – 11:45AM    Katharina Ribbeck (Massachusetts Institute of Technology) – Mucin glycans attenuate microbial virulence. #11
Poster Talks
11:45AM – 11:50AM    Atossa C. Ghorashi (University of Texas Southwestern Medical Center) – Characterizing the role of host fucose in cholera toxin action. #12/B006
11:50AM – 11:55AM    Anna Blenda and Nourine Kamili (USC School of Medicine Greenville and Emory University School of Medicine) – Distinct antimicrobial properties of the N- and C- terminal domains of the human protein galectin-9. #13/B007
11:55AM – 12:00PM     Joanna Coker (University of California San Diego) – Bacterial community manipulation through glycan-lectin interactions. #14/B008
12:00PM – 12:05PM     Sun-Mi Choi (University of California San Diego) – Staphylococcus Aureus Exacerbates Epithelial Barrier Dysfunction in Chronic Rhinosinusitis. #15/B009
12:05PM – 12:10PM     Mathias Braun (University of Natural Resources and Life Sciences, Vienna) – A conserved glycosyltransferase from the general protein O-glycosylation pathway of Bacteroidetes. #16/B010
12:10PM – 12:15PM     Sohyoung Lee (Cornell University) – Host adaptations of the Salmonella Typhi typhoid toxin and its orthologue from a nontyphoidal Salmonella. #17/B011
12:15PM – 01:30PM          Lunch on your own
12:15PM – 01:30PM          Glycobiology Editorial Board Meeting (by invitation only)
                                           Salons 7 & 8
01:30PM – 04:00PM   Poster Session I and Exhibits
                                           Pueblo Ballroom
04:00PM – 05:45PM   Session 3: Glycotechnology, a translational perspective
                                           Session chair: Parastoo Azadi (University of Georgia CCRC)
                                           North Ballroom
04:00PM – 04:25PM     Max Crispin (University of Southampton) – Glycosylation of enveloped viruses: structure and immunogen design. #18
04:25PM – 04:50PM     Laurence Mulard (Institut Pasteur, France) – Synthetic oligosaccharide-based conjugate vaccines against shigellosis: from concept and design to first-in-human study. #19
04:50PM – 05:15PM     Fredrik Zetterberg (Galecto Biotech, Denmark) – Translational aspects of drug discovery and development: TD139 case story, a small molecule Galectin 3 inhibitor in phase 2b trials against IPF. #20
Poster Talks
05:15PM – 05:20PM     Stacy A. Malaker (Stanford University) – Enzyme toolkit for selective enrichment and analysis of mucin-domain glycoproteins. #21/B012
05:20PM – 05:25PM     Uriel Ortega-Rodriguez (University of Texas at El Paso) – Structural characterization of T. cruzi Epimastigote Glycosylphosphatidylinositol-Mucin sialoglycans. #22/B013
05:25PM – 05:30PM     Sriram Neelamegham (State University of New York- Buffalo) – Tuning metabolic decoy efficacy by modifying the linkage between carbohydrate and aglycone. #23/B014
05:30PM – 05:35PM     Manuela Mally (LimmaTech Biologics AG, Switzerland) – CustomGlycan: A novel platform for production of therapeutics. #24/B015
05:35PM – 05:40PM     Jonathon E. Mohl (University of Texas El Paso) – Identification and design of transferase specific mucin-type O-glycosylation peptides using ISOGlyP’s selective peptide function. #25/B016
05:40PM – 05:45PM     Akshi Singla (Texas A&M University) – Glycolipid-based targeted drug delivery system against multidrug resistant Pseudomonas aeruginosa. #26/B017
05:45PM – 06:45PM   Innovator Award Lecture
                                           North Ballroom
Gerald Hart (Complex Carbohydrate Research Center, UGA)

DAY 3: Monday, Nov 4, 2019

08:00AM – 02:00PM         Registration
                                           Ballroom Foyer
07:30AM – 08:30AM         Continental Breakfast
                                           Ballroom Foyer
08:30AM – 10:15AM         Session 4: Systems Biology approaches to Glycobiology
                                           Session chair: Thierry Hennet (University of Zurich)
                                           North Ballroom
08:30AM – 08:55AM    Morten Thaysen-Andersen (Macquarie University) – Uncovering New Aspects of Neutrophil Glycobiology using Glyco(proteo)mics. #27
08:55AM – 09:20AM    Nathan E. Lewis (UC San Diego) – The cellular impact of glycoengineering. #28
09:20AM – 09:45AM    Ryan Weiss (UC San Diego, Esko-Laboratory) – Genome-wide Regulation of Heparan Sulfate Assembly. #29
Poster Talks
09:45AM – 09:50AM    Ronghu Wu (Georgia Institute of Technology) – Mass Spectrometry-Based Chemical and Enzymatic Methods for Global Analysis of Protein Glycosylation in Complex Biological Samples. #30/B018
09:50AM – 09:55AM    Benjamin L. Schulz (The University of Queensland) – SWATH glycoproteomics to interrogate post-translational modification dynamics in yeast and sparkling wine. #31/B019
09:55AM – 10:00AM    Yusen Zhou (University at Buffalo, SUNY) – Integrating Mass Spectrometry and RNA-Seq data for Glycosylation Pathway Generation and Simulation. #32/B020
10:00AM – 10:05AM    Steve M. Fernandes (Johns Hopkins University School of Medicine) – Comparative sialoglycan microarray analyses of selected human and mouse Siglecs. #33/B021
10:05AM – 10:10AM    Kiyoko F. Aoki-Kinoshita (Soka University) – The GlyCosmos Portal as a part of the GlySpace Alliance: towards an international glyco-data science collaboration environment. #34/B022
10:10AM – 10:15AM    Shu Zhang (Zhongshan Hospital, Fudan University) – N-glycopeptide signatures of IgA2 in serum from patients with hepatitis B virus-related liver diseases. #55/B035
10:15AM – 10:30AM         Coffee Break
                                           Ballroom Foyer
10:30AM – 12:10PM         Session 5: Regulatory functions of glycans
              Session chair: Lance Wells (University of Georgia, BCMB)
              North Ballroom
10:30AM – 10:55AM          Jürgen Lassak (Ludwig-Maximilians University Munich, Germany) – An odd couple? – Arginine and rhamnose form a novel glycoconjugate to rescue bacterial translation. #35
10:55AM – 11:20AM          John Allan Hanover (National Institutes of Health) – Critical roles for O-GlcNAc in Metabolic Signaling, Stem Cell Biology, and DNA damage repair. #36
11:20AM – 11:45AM          Natasha E. Zachara (Johns Hopkins School of Medicine) – Decoding the role of intracellular glycosylation in cytoprotection and disease. #37
Poster Talks
11:45AM – 11:50AM    Yanzhuang Wang (University of Michigan) – GRASP55 senses energy and nutrient deprivation through O-GlcNAcylation to promote autophagosome-lysosome fusion. #38/B023
11:50AM – 11:55AM    Adam J. Kanack (Medical College of Wisconsin) – Platelet and myeloid cell phenotypes in a rat model of Fabry disease. #39/B024
11:55AM – 12:00PM     Brett E. Crawford (BioMarin Pharmaceutical) – Discovery of novel ceramide galactosyltransferase inhibitors and their therapeutic application to Krabbe disease. #40/B025
12:00PM – 12:05PM     Seung Yeop Han (Baylor College of Medicine) – A Conserved Role for N-Glycanase 1 in Regulating Energy Metabolism through AMPK signaling. #41/B026
12:05PM – 12:10PM     Angelica M. Gomes Ueltschy (Cleveland Clinic) – Glucose homeostasis is regulated by hyaluronan synthases 1 and 3. #42/B027
12:10PM – 01:30PM          Lunch on your own
01:30PM – 04:00PM   Poster Session II and Exhibits
                                           Pueblo Ballroom
04:00PM – 04:45PM   Society Business Meeting
                                           North Ballroom
04:45PM – 06:15PM   MCP and Significant Achievement Award Lecture
                                           North Ballroom
Manfred Wuhrer (Leiden University Medical Center) – MCP Award Lecture
Jochen Zimmer (University of Virginia) – Significant Achievement Award Lecture
06:15PM – 07:00PM          Break
07:00PM – 11:00PM   Banquet
                                       North Ballroom

DAY 4: Tuesday Nov 5, 2019

08:00AM – 12:00PM         Registration
                                           Ballroom Foyer
07:30AM – 08:30AM         Continental Breakfast
08:30AM – 10:10AM  Session 6: Glycobiology of Mammalian development and Stem cells
                                           Session chair: Jeffrey D. Esko (UC San Diego)
                                           North Ballroom
08:30AM – 08:55AM    Jamey Marth (UC Santa Barbara) – Glycoprotein aging and turnover in the pathogenesis of disease. #43
08:55AM – 09:20AM    Pamela Stanley (Albert Einstein College of Medicine) – An Inhibitor of N-glycan Maturation in Mouse                                Germ Cells. #44
09:20AM – 09:45AM    Hans Wandall (University of Copenhagen) – Contextualized Functions of Glycans in Tissue Formation. #45
Poster Talks
09:45AM – 09:50AM    Ilhan Akan (National Institute of Health) – Oga mutants reveal epigenetic, transcriptional and metabolic factors effecting life span and body size in Drosophila. #46/B028
09:50AM – 09:55AM    Frank Leon (University of Nebraska Medical Center) – Role of Immature CD44 O-glycosylation and its Activation of Targets Responsible for Stemness Properties of Pancreatic Cancer. #47/B029
09:55AM – 10:00AM    Vladislav Panin (Texas A&M University) – Role of sialylation in the control of cardiac functions in Drosophila. #48/B030
10:00AM – 10:05AM    Yang Yang (Georgetown University) – SULF2 overexpression affects survival and modulates sulfation of heparan sulfate proteoglycans in Squamous Cell Carcinoma of the Head and Neck . #49/B031
10:05AM – 10:10AM    Yan Wang (Cleveland Clinic) – Enhanced myofibroblast differentiation in Hyaluronan Synthase1/3 double knockout mice is independent of hyaluronan and mediated by a TGFβR/p38MAPK/MRTF pathway. #50/B032
10:10AM – 10:30AM         Coffee Break
                                           Ballroom Foyer
10:30AM – 11:45AM  Session 7: Glycobiology of the Immune System
                                           Session chair: Richard Cummings (Harvard Medical School)
                                           North Ballroom
10:30AM - 10:55AM     Jim Paulson (Scripps Research, La Jolla) – Siglecs as checkpoints in immune cell responses. #51
10:55AM - 11:20AM     Avery Posey (University of Pennsylvania) – Reprogramming T cells to target glycopeptide epitopes and glycolipids for effective cancer therapy.. #52
Poster Talks
11:20AM – 11:25AM    Marija Pezer (Genos Glycoscience Research Laboratory) – Immunoglobulin G glycosylation changes in diseases and aging. #53/B033
11:25AM – 11:30AM    Damien Restagno (University California Santa Barbara) – Glycoprotein Aging with Increased Mannose Exposure Linked to Cardiovascular Disease through the Macrophage Mannose Receptor (Mrc1) . #54/B034
11:30AM – 11:35AM    Jiaxuan Chen (Beth Israel Deaconess Medical Center) – Resident and Elicited Macrophages Differ in Expression of their Glycomes and Lectins. #56/B036
11:35AM – 11:40AM    Vivianne I. Otto (ETH Zurich) – The particular glycomes of lymph node lymphatic endothelia and their role in localization and activation of Siglec-1+ subcapsular sinus macrophages. #57/B037
11:40AM – 11:45AM    Melissa M. Lee-Sundlov (Blood Research Institute, Versiti) – Megakaryocyte O-glycan sialylation regulates platelet production through interferon-secreting plasmacytoid dendritic cells. #58/B038
11:45AM – 01:30PM         Lunch on your own
01:30PM – 03:10PM   Session 8: Glycobiology of Cancer
                                           Session chair: Pamela Stanley (Albert Einstein College of Medicine)
                                           North Ballroom
01:30PM – 01:55PM     Robert Sackstein (Florida International University) – E-Selectin Ligands in Human Leukemogenesis. #59
01:55PM – 02:20PM     Susan Bellis (UAB School of Medicine, Birmingham) – ST6Gal-I sialyltransferase promotes pancreatic cancer progression through imparting a cancer stem cell phenotype. #60
02:20PM – 02:45PM     Heinz Läubli (University of Basel, Dep of Biomedicine) – Targeting the sialoglycan–Siglec axis augments antitumor immunity allowing effective PD-1 and CTLA-4 blockade. #61
Poster Talks
02:45PM – 02:50PM     Yasuyuki Matsumoto (Beth Israel Deaconess Medical Center- Harvard Meidcal Center) – Identification of Novel Glycoproteins with Defined anti-Tn IgG and IgM; Applications as Tumor Diagnostic Biomarkers. #62/B039
02:50PM – 02:55PM     Rachel A. Willand-Charnley (South Dakota State University) – Modulation of Siglec Binding Via SIAE and CASD1-An Immune Evasion Pathway for Breast and Colon Cancers. #63/B040
02:55PM – 03:00PM     Su-Ryun Kim (Food and Drug Administration) – The Role of Core 3 β3-N-Acetylglucosaminyltransferase in Colorectal Cancer. #64/B041
03:00PM – 03:05PM     Kathrin Stavenhagen (Beth Israel Deaconess Medical Center- Harvard Medical Center) – Endogenous Ligands of The Mannose Receptor C-Type Lectin Domain in Cancer And Control Tissue. #65/B041
03:05PM – 03:10PM     Ryan N. Porell (University of California San Diego) – Reprogramming the Tumor Microenvironment with Macrophage-Targeted Glycopolymers. #66/B043
03:10PM – 03:15PM    Closing Remarks


04:00 - 07:00PM           K12 Meeting

NHLBI recently funded four K12 training grants across the US. Our purpose is to attract physician scientists and post-doctoral fellows to the field and provide comprehensive classroom and laboratory training.
• Johns Hopkins-Cleveland Clinic Program for Career Development in Glycosciences
• BloodCenter of Wisconsin Program for Career Development in Glycosciences
• Harvard Program for Career Development in Glycosciences
• UC San Diego Program for Career Development in Glycosciences